SEVERAL ASPECTS OF DILTIAZEM AND ORGANIC NITRATES USAGE IN VARIOUS SEVERITY STABLE ANGINA PATIENTS
نویسندگان
چکیده
منابع مشابه
Combination treatment with trimetazidine and diltiazem in stable angina pectoris.
OBJECTIVE To assess antianginal efficacy and possible adverse haemodynamic effects of combination treatment with trimetazidine and diltiazem in patients with stable angina. DESIGN Double blind, randomised, placebo controlled trial of four weeks duration. SETTING Outpatient department of two Indian hospitals. SUBJECTS 64 male patients with stable angina, uncontrolled on diltiazem alone. ...
متن کاملBeneficial effects of diltiazem and propranolol, alone and in combination, in patients with stable angina pectoris.
The antianginal effects of diltiazem 180 mg/day and propranolol 240 mg/day, alone and in combination, were investigated in 15 patients with effort related angina in a double blind placebo controlled crossover trial, with each period of treatment lasting four weeks. Patients performed a symptom limited treadmill exercise test at the end of each period of treatment. Mean (SEM) time to onset of an...
متن کاملObjective evaluation of three dose levels of diltiazem in patients with chronic stable angina.
Twenty-one patients with chronic stable angina were treated with the calcium antagonist diltiazem. Dose titration studies involving 180, 270 and 360 mg/day were conducted using a blinded objective protocol. Improvement in exercise tolerance was observed at all dose levels, but the best reduction of anginal attacks and glyceryl trinitrate consumption, enhancement of exercise capacity and improve...
متن کاملIncreased exercise tolerance and reduced electrocardiographic ischemia with diltiazem in patients with stable angina pectoris.
Diltiazem is a calcium slow-channel blocking drug that may be effective in the treatment of chronic stable angina pectoris. To evaluate the therapeutic efficacy 3 hours after a single oral dose of 120 mg, 12 men with chronic stable angina pectoris performed a maximal exercise test on a bicycle ergometer after ingesting either placebo or diltiazem administered in a double-blind fashion. During s...
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در این پروژه ترکیبات 3-آریل-2h-بنزو[b]-4،1-اکسازین ها از مواد اولیه تجاری مشتقات دو آمینو فنول و ?-هالو کتون های آروماتیک در مایع یونی 1-اکتیل-3-متیل ایمیدازولیوم تترا فلورو بورات([omim]bf4) سنتز شده است. این واکنش توسط باز پتاسیم کربنات محلول از طریق o-آلکیلاسیون و سپس یک واکنش آمیداسیون درون مولکولی خود بخود در مدت زمان کوتاه انجام می شود. ترکیبات 4،1-بنزوکسازین به این روش با بهره خوب تا آلی ...
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ژورنال
عنوان ژورنال: Cardiovascular Therapy and Prevention
سال: 2014
ISSN: 2619-0125,1728-8800
DOI: 10.15829/1728-8800-2014-2-18-23